The Promus Pathway is a revolutionary comprehensive molecular test that combines the rapid pathogen identification of PCR technology with established CFU/ml reporting methodologies making results more relevant, meaningful and reliable.
brings the next evolution in PCR testing
The Promus Pathway is the next level of PCR reporting. Promus Pathway identifies and reports 30+ of the most relevant pathogens and 20+ antibiotic resistant genes in the established CFU/ml reporting methodology. Promus Pathway’s CFU/ml reporting delivers faster, more comprehensive, and accurate treatment guidance (drug, dosage and duration) compared to C&S or standard PCR options. Unlike C&S which is only 57% accurate and takes as much as 72 hours, Promus Pathway produces test results in just 24 hours with 95%+ accuracy, eliminating the need to treat patients empirically and insuring the best possible antibiotic stewardship.
Promus is the only PCR lab to identify, isolate and design methods to proliferate over 100 live pathogens across multiple infectious disease assays and create a validated reporting algorithm that couples highly accurate results in CFUs/mL and all related antibiotic resistance genes. Promus is able to provide the only fully validated antibiotic treatment guidance that is easily translated into standard antibiotic dosing protocols for each pathogen and the associated antibiotic resistance genes.
A Complete Testing Solution for the Entire Body
The unique testing technology of the Promus Pathway allows for rapid identification and quantification of pathogens across all of the body systems, encompassing eight key panels, each tailored to provide valuable insights into different health aspects. From detecting urinary tract infections and respiratory pathogens to assessing wound infections and gastrointestinal issues, Promus Pathway provides the accurate diagnostic information you can trust.
How Other Labs Test for Bacterial Infections
The Importance of Antibiotic Stewardship
Antibiotic resistance refers to the ability of an infection causing bacteria to resist the effects of antibiotics. According to the CDC, “each year in the United States at least 2.8 million antibiotic-resistant infections occur, and more than 35,000 people die as a result.” (CDC.gov) Antibiotic resistance stems from the misuse of antibiotics – either by prescribing the incorrect type of antibiotic to fight a particular pathogen, administering antibiotics when they are not actually needed, using the incorrect dosage, or by not taking the antibiotic for the proper duration.
The effort among providers, hospitals, laboratories, and government agencies to address antibiotic resistance and prevent overuse or misuse of antibiotics is called “antibiotic stewardship.”
‘Silent pandemic’ warning from WHO: Bacteria killing too many people due to antimicrobial resistance
https://www.foxnews.com/health/silent-pandemic-warning-who-bacteria-killing-too-many-people-antimicrobial-resistance
Antimicrobial Resistance Information from FDA
https://www.fda.gov/emergency-preparedness-and-response/mcm-issues/antimicrobial-resistance-information-fda
Core Elements of Antibiotic Stewardship
https://www.cdc.gov/antibiotic-use/core-elements/index.html
From 2010 to 2015,of 670,450 women with uncomplicated UTI, a large proportion received antibiotic prescriptions for inappropriate agents (46.7%) or durations (76.1%)
Antimicrobial Resistance and Its Spread Is a Global Threat
https://www.mdpi.com/2079-6382/11/8/1082
“Antibiotic stewardship is the effort to measure and improve how antibiotics are prescribed by clinicians and used by patients.”2
Urinary Tract Infection
+ Antibiotic Resistance Genes (UTI+ABR)
Promus Diagnostics Molecular PCR UTI Test is the Solution
Urinary Tract Infections (UTI) are the most common bacterial infection among long term care residents and the second most common infection diagnosed in the acute hospital setting. UTIs account for almost 5% of all emergency department visits by adults aged 65 years and older in the United States each year.
Traditional testing for a UTI involves a urine culture which can take days to complete, greatly reducing sensitivity and accuracy. Without an accurate identification of the pathogen, healthcare providers may treat the patient with a course of antibiotics that may not be the optimal choice based on pathogens present resulting in persistent or recurring UTIs.
A recent study by Washington University found that of the 670,450 women tested, 46.7% “received antibiotic prescriptions for inappropriate agents” and 76.1% received antibiotics for an incorrect duration.1
At Promus Diagnostics we provide a better solution for identifying the pathogens causing an UTI using real-time PCR technology. Our UTI+ABR test panel can quickly and accurately identify 31 different infection causing pathogens and 22 antimicrobial resistance markers, giving healthcare providers the clearest and most robust information to develop a treatment regimen.
Identification where culture or dipstick may not have detected infection, or inconclusive due to sample contamination
Reduce or eliminate recurrent infections based on superior identification of Uropathogens for proper treatment
Informed drug selection to remediate infection, decrease incidents of adverse events as well as lessen the potential for antibiotic resistance
