The Evolution of Molecular PCR for Infectious Diagnostics

The Promus Pathway is a revolutionary comprehensive molecular test that combines the rapid pathogen identification of PCR technology with established CFU/ml reporting methodologies making results more relevant, meaningful and reliable.

brings the next evolution in PCR testing

The Promus Pathway is the next level of PCR reporting. Promus Pathway identifies and reports 30+ of the most relevant pathogens and 20+ antibiotic resistant genes in the established CFU/ml reporting methodology. Promus Pathway’s CFU/ml reporting delivers faster, more comprehensive, and accurate treatment guidance (drug, dosage and duration) compared to C&S or standard PCR options. Unlike C&S which is only 57% accurate and takes as much as 72 hours, Promus Pathway produces test results in just 24 hours with 95%+ accuracy, eliminating the need to treat patients empirically and insuring the best possible antibiotic stewardship.

Promus is the only PCR lab to identify, isolate and design methods to proliferate over 100 live pathogens across multiple infectious disease assays and create a validated reporting algorithm that couples highly accurate results in CFUs/mL and all related antibiotic resistance genes. Promus is able to provide the only fully validated antibiotic treatment guidance that is easily translated into standard antibiotic dosing protocols for each pathogen and the associated antibiotic resistance genes.

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Promus Pathway Flyer
Promus Pathway vs. Culture or Standard PCR
Promus Pathway Patient Brochure
UTI Panel Sample Report

A Complete Testing Solution for the Entire Body

The unique testing technology of the Promus Pathway allows for rapid identification and quantification of pathogens across all of the body systems, encompassing eight key panels, each tailored to provide valuable insights into different health aspects. From detecting urinary tract infections and respiratory pathogens to assessing wound infections and gastrointestinal issues, Promus Pathway provides the accurate diagnostic information you can trust.


This panel examines samples from the ear, nose, or throat to identify pathogens causing infections. It aids in diagnosing conditions like ear infections, sinusitis, or strep throat.

Respiratory (RPP)

The respiratory panel is a comprehensive test that analyzes respiratory secretions to detect various viral and bacterial pathogens. It aids in diagnosing respiratory infections and guiding appropriate treatment.


This panel is used to evaluate wound infections by analyzing samples taken from the affected area. It helps identify specific pathogens and provides essential information for proper wound care.


The gastrointestinal panel examines stool samples to detect various bacterial, viral, and parasitic pathogens responsible for gastrointestinal infections. It assists in diagnosing and managing digestive health issues.

Women’s Health

The women’s health panel is designed to assess female reproductive health by analyzing various markers, including hormone levels and infections, providing valuable insights for women’s well-being.


This panel tests for common sexually transmitted infections (STIs) like chlamydia, gonorrhea, syphilis, and others. It plays a crucial role in early detection and treatment of STIs, promoting sexual health and well-being.

Urinary Tract Infection

Our UTI+ABR test panel can quickly and accurately identify 31 different infection causing pathogens and 22 antimicrobial resistance markers, giving healthcare providers the clearest and most robust information to develop a treatment regimen.

Nail & Hair

This diagnostic test assesses nail and hair samples for fungal or bacterial infections. It helps identify the cause of nail or scalp issues for appropriate treatment.

How Other Labs Test for Bacterial Infections

Culture & Sensitivity

For over 50 years Culture and Sensitivity (“C&S”) has been considered the traditional “gold standard” to identify, diagnose and treat complicated bacterial infections. While C&S reports results in Colony Forming Units (CFU/ml) to provide treatment guidance (drug dosage and duration), C&S does not grow, identify or report ALL of the relevant pathogens in a specimen. The result is that some pathogens go undetected and untreated. Additionally, C&S requires up to 72 hours to complete. As a consequence, C&S prescribers treat patients empirically adding to globally recognized “antibiotic stewardship” risks.

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Standard PCR

Most PCR labs identify 15-20 relevant pathogens, 2-10 Antibiotic Resistant Genes and report results in 24-48 hours. While this is faster and more comprehensive than C&S, there are more than a dozen additional pathogens and resistant genes that most labs fail to detect and consequently will not be treated by the medical provider. More importantly, other labs report results in DNA copies/mL not CFU/ml. Unlike CFU/ml, DNA copies/ml is not consistent with established reporting methodology and offers limited diagnostic treatment guidance to the provider.

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The Importance of Antibiotic Stewardship

Antibiotic resistance refers to the ability of an infection causing bacteria to resist the effects of antibiotics. According to the CDC, “each year in the United States at least 2.8 million antibiotic-resistant infections occur, and more than 35,000 people die as a result.” ( Antibiotic resistance stems from the misuse of antibiotics – either by prescribing the incorrect type of antibiotic to fight a particular pathogen, administering antibiotics when they are not actually needed, using the incorrect dosage, or by not taking the antibiotic for the proper duration.

The effort among providers, hospitals, laboratories, and government agencies to address antibiotic resistance and prevent overuse or misuse of antibiotics is called “antibiotic stewardship.”

“Antibiotic stewardship is the effort to measure and improve how antibiotics are prescribed by clinicians and used by patients.”2

Urinary Tract Infection
+ Antibiotic Resistance Genes (UTI+ABR)

Promus Diagnostics Molecular PCR UTI Test is the Solution

Urinary Tract Infections (UTI) are the most common bacterial infection among long term care residents and the second most common infection diagnosed in the acute hospital setting. UTIs account for almost 5% of all emergency department visits by adults aged 65 years and older in the United States each year.

Traditional testing for a UTI involves a urine culture which can take days to complete, greatly reducing sensitivity and accuracy. Without an accurate identification of the pathogen, healthcare providers may treat the patient with a course of antibiotics that may not be the optimal choice based on pathogens present resulting in persistent or recurring UTIs.

A recent study by Washington University found that of the 670,450 women tested, 46.7% “received antibiotic prescriptions for inappropriate agents” and 76.1% received antibiotics for an incorrect duration.1

At Promus Diagnostics we provide a better solution for identifying the pathogens causing an UTI using real-time PCR technology. Our UTI+ABR test panel can quickly and accurately identify 31 different infection causing pathogens and 22 antimicrobial resistance markers, giving healthcare providers the clearest and most robust information to develop a treatment regimen.

Improper diagnosis or ineffective treatment plan for a UTI could cause
  • Permanent kidney damage
  • Life-threatening sepsis
  • Ongoing discomfort
  • Chronic infections

Identification where culture or dipstick may not have detected infection, or inconclusive due to sample contamination

Reduce or eliminate recurrent infections based on superior identification of Uropathogens for proper treatment

Informed drug selection to remediate infection, decrease incidents of adverse events as well as lessen the potential for antibiotic resistance